RET/TRKA-IN-1

Product Description: RET/TRKA-IN-1 (Compound 13) is a dual inhibitor for RET (IC50=0.375 µM) and TRKA. RET/TRKA-IN-1 inhibits cell viability of LC-2 and KM12, with GI50 of 0.72 and 0.25 μM. RET/TRKA-IN-1 arrests the cell cycle at G1 phase[1].

Formula: C30H31N9O

References: [1]Acharya B, et al., Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors. Bioorg Med Chem. 2024 May 15;106:117749.

Molecular Weight: 533.63

Research Area: Cancer

Target: RET;Trk Receptor

• Artikelnummer: MEXHY-161775-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161775-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK