SB-215505, CAS 162100-15-4

Product Description: SB-215505 is a potent and subtype-selective 5-HT2B receptor antagonist with pKi values of 8.3, 6.77, 7.66 for 5-HT2B, 5-HT2A, 5-HT2C, respectively[1]. SB-215505 increases wakefulness and motor activity in rats[2].

Applications: Neuroscience-Neuromodulation

Formula: C19H16ClN3O

References: [1]C Reavill, et al. Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist. Br J Pharmacol. 1999 Feb;126(3):572-4./[2]Sandor Kantor, et al. Increased wakefulness, motor activity and decreased theta activity after blockade of the 5-HT2B receptor by the subtype-selective antagonist SB-215505. J Pharmacol. 2004 Aug;142(8):1332-42.

CAS Number: 162100-15-4

Molecular Weight: 337.80

Compound Purity: 98.91

Research Area: Neurological Disease

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: 5-HT Receptor

• Artikelnummer: MEXHY-18596-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18596-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK