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Product Description: SIRP-beta (Sirpb, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins, Sirpb was found to interact with TYROBP/DAP12, a transmembrane adaptor protein bearing immunoreceptor tyrosine-based activation motifs, resulting in the tyrosine phosphorylation of DAP12 and the subsequent recruitment of Syk to the Sirpb-DAP12 complex. Sirpb is also implicated as a positive regulator of hematopoietic cells. SIRP beta Protein, Mouse (HEK293, His) is the recombinant mouse-derived SIRP beta protein, expressed by HEK293 , with C-His labeled tag.Artikelnummer | MEXHY-P77490A-10UG |
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Hersteller | MedChemExpress |
Hersteller Artikelnummer | HY-P77490A-10UG |
Verpackungseinheit | 10 μg |
Mengeneinheit | STK |
Produktinformation (PDF) |
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MSDS (PDF) |
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