SSR126768A (free base), CAS 785048-28-4

Product Description: SSR126768A free base is an orally active antagonist for oxytocin receptor, with Ki of 0.44 nM. SSR126768A free base is a tocolytic agent, that antagonizes the Oxytocin (HY-17571)-induced intracellular Ca2+ increase and prostaglandin release in human uterine smooth muscle cells, inhibits thus the Oxytocin (HY-17571)-induced uterine contraction and delays parturition in pregnant rats in labor[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C33H31Cl2N3O4

References: [1]Serradeil-Le Gal C, et al., SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor. J Pharmacol Exp Ther. 2004 Apr;309(1):414-24.

CAS Number: 785048-28-4

Molecular Weight: 604.52

Research Area: Endocrinology

Target: Oxytocin Receptor

• Artikelnummer: MEXHY-15018A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15018A-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK