SUN-1334H (free base), CAS 607737-00-8

Product Description: SUN-1334H free base is an orally active inhibitor for histamine H1 receptor, with an IC50 of 20.3 nM and Ki of 9.7 nM. SUN-1334H free base inhibits histamine-induced contractions of isolated guinea-pig ileum with an IC50 of 0.198 μM. SUN-1334H free base inhibits histamine-induced bronchoconstriction in guinea pigs, histamine-induced skin wheals in beagle dogs, and ovalbumin-induced rhinitis in guinea pigs[1].

Applications: COVID-19-immunoregulation

Formula: C23H26F2N2O3

References: [1]Mandhane SN, et al., Preclinical efficacy and safety pharmacology of SUN-1334H, a potent orally active antihistamine agent. Drugs R D. 2008;9(2):93-112.

CAS Number: 607737-00-8

Molecular Weight: 416.46

Research Area: Inflammation/Immunology; Cardiovascular Disease

Target: Adrenergic Receptor;Dopamine Receptor;Histamine Receptor;Sigma Receptor

• Artikelnummer: MEXHY-164010-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-164010-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK