TAK-448, CAS 1234319-68-6

Product Description: TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1].

Applications: Cancer-programmed cell death

Formula: C58H80N16O14

References: [1]1.Nishizawa N, et al. Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly PotentTestosterone-Suppressive Activity and Excellent Water Solubility. J Med Chem. 2016 Oct 13;59(19):8804-8811./[2]Ishikawa K,et al. Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitiveprostate cancer model. Eur J Pharmacol. 2018 Jun 5;828:126-134.

CAS Number: 1234319-68-6

Molecular Weight: 1225.36

Compound Purity: 99.92

Research Area: Cancer

Solubility: H2O : 100 mg/mL (ultrasonic)

Target: Kisspeptin Receptor

• Artikelnummer: MEXHY-P0076-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P0076-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK