Product Description: TAT-GluR6-9c is a GluR6-PSD95 interaction blocker. By regulating the GluR6 mediated signaling pathway, TAT-GluR6-9c inhibits the activation of JNK and phosphorylation of c-Jun, reduces the expression of Fas L and thus reduces the occurrence of apoptosis. TAT-GluR6-9c can be used to study cerebral ischemia and neuroprotective strategies [1].
Applications: Neuroscience-Neurodegeneration
Formula: C106H191N45O26S
References: [1]Pei D S, et al. Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence[J]. Brain, 2006, 129(2): 465-479.
Molecular Weight: 2544.00
Research Area: Neurological Disease; Cardiovascular Disease
Target: Apoptosis;iGluR