Product Description: Thiocoraline is a depsipeptide that can be isolated by marine Micromonospora. Thiocoraline has antitumor activity with IC50s of 0.002, 0.002, 0.01 and 0.002 μg/mL in P388, A549, HT-29 and MEL-28 cells, respectively. Thiocoraline also a strong antimicrobial activity against Gram-positive microorganisms[1].
Applications: Cancer-programmed cell death
Formula: C48H56N10O12S6
References: [1]Romero F, et al. Thiocoraline, a new depsipeptide with antitumor activity produced by a marine Micromonospora. I. Taxonomy, fermentation, isolation, and biological activities. J Antibiot (Tokyo). 1997 Sep;50(9):734-7.
CAS Number: 173046-02-1
Molecular Weight: 1157.41
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Bacterial