TK-642, CAS 2765183-10-4

TK-642, CAS 2765183-10-4
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MEXHY-158762-0
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MedChemExpress

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Product Description: TK-642 is a highly active, selective, orally activity SHP2 inhibitor based on pyrazole and pyrazine (IC50=2.7 nmol/L). TK-642 can effectively inhibit the proliferation of esophageal carcinoma cells and induce cell apoptosis. TK-642 can be used in the study of esophageal cancer[1].

Applications: Cancer-Kinase/protease

Formula: C17H20ClN7S

References: [1]Tang K, et al. Discovery of TK-642 as a highly potent, selective, orally bioavailable pyrazolopyrazine-based allosteric SHP2 inhibitor[J]. Acta Pharmaceutica Sinica B, 2024.

CAS Number: 2765183-10-4

Molecular Weight: 389.91

Research Area: Cancer

Target: SHP2
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Artikelnummer MEXHY-158762-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-158762-0
Verpackungseinheit Get quote
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