Valsartan methyl ester, CAS 137863-17-3

Product Description: Valsartan methyl ester (Compound 3) is a derivative of Valsartan (HY-18204). Valsartan methyl ester is an orally active antagonist for angiotensin II, that inhibits angiotensin II (IC50 of 0.06 μM), angiotensin II-induced pressor response in rabbit aorta (IC50 of 0.068 μM) and angiotensin II-induced pressor response in the pithed rat model (10% inhibition at 10 mg/kg, p.o.)[1].

Formula: C25H31N5O3

References: [1]Bühlmayer P, et al., Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series[J]. Bioorganic & Medicinal Chemistry Letters, 1994, 4(1): 29-34.

CAS Number: 137863-17-3

Molecular Weight: 449.55

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Angiotensin Receptor

• Artikelnummer: MEXHY-W414915-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W414915-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK