Vatinoxan, CAS 114914-42-0

Product Description: Vatinoxan (MK-467) is an alpha 2-adrenergic receptor antagonist. The peripheral selectivity of Vatinoxan determines that it has limited penetration across the blood-brain barrier and therefore has low concentrations in the central nervous system. Vatinoxan antagonizes alpha 2-adrenergic receptor receptors by binding to them, thereby reducing or preventing cardiovascular effects caused by α2-adrenergic agonists. Vatinoxan can be used in studies of cardiovascular effects, sedation and analgesia[1].

Applications: Neuroscience-Neuromodulation

Formula: C20H26N4O4S

References: [1]Honkavaara J M, et al. Concentrations of medetomidine enantiomers and vatinoxan, an α2-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs[J]. Veterinary anaesthesia and analgesia, 2020, 47(1): 47-52.

CAS Number: 114914-42-0

Molecular Weight: 418.51

Research Area: Neurological Disease; Cardiovascular Disease

Target: Adrenergic Receptor

• Artikelnummer: MEXHY-19057-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-19057-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK