Product Description: VEGFR-2/AKT-IN-1 (compound 17) is a dual inhibitor of VEGFR-2 and AKT, with the IC50s of 0.164 μM and 0.452 μM, respectively. VEGFR-2/AKT-IN-1 has antitumor activity[1].
Formula: C16H11N9OS2
References: [1]Heba K Abd El-Mawgoud, et al. Design, synthesis and cytotoxic evaluation of new thieno[2,3-d]pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers. Bioorg Chem. 2024 Sep:150:107622.
Molecular Weight: 409.45
Research Area: Cancer
Target: Akt;VEGFR