VEGFR-2/STAT-3-IN-1

Product Description: VEGFR-2/STAT-3-IN-1 (Compound 9f) is a dual inhibitor for VEGFR-2 (IC50=26.3 nM) and STAT-3 (IC50=5.63 nM). VEGFR-2/STAT-3-IN-1 inhibits the proliferation of cancer cells PANC1 and PC3 with IC50 of 0.14 and 0.10 µM. VEGFR-2/STAT-3-IN-1 induces apoptosis in PC3[1].

Applications: Cancer-Kinase/protease

Formula: C26H20N6O4

References: [1]Elsebaie HA, et al., Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessments. Bioorg Chem. 2024 Jul 10;151:107626.

Molecular Weight: 480.47

Research Area: Cancer

Target: STAT;VEGFR

• Artikelnummer: MEXHY-161859-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161859-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK