VPM-p15

Product Description: Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6). The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members[1].

Formula: C75H126N18O22

References: [1]Sun Y, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology[J]. Journal of Biological Chemistry, 2021, 296.

Molecular Weight: 1631.91

Compound Purity: 98.18

Research Area: Others

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-P10365-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10365-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK