Product Description: WAY-100289 is an orally active antagonist for 5-HT3 receptor, that exhibits high affinity to the isolated rat vagus nerves with pA2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats[1].
Formula: C20H27N3O3
References: [1]Rhodes K F, et al. WAY 100289: Pharmacological profile of a novel 5‐HT3 receptor antagonist[J]. Drug development research, 1993, 28(2): 128-140.
CAS Number: 136013-69-9
Molecular Weight: 357.45
Research Area: Neurological Disease
Target: 5-HT Receptor