2′-O-(2-Methoxyethyl)guanosine, CAS 473278-54-5

Product Description: 2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2].

Formula: C13H19N5O6

References: [1]McPherson AK, et, al. An Improved Process for the Manufacture of 5′-O-(4,4′-Dimethoxytrityl)-N2-isobutyryl-2′-O-(2-methoxyethyl)guanosine. Org. Process Res. Dev. 2020, 24, 11, 2583-2590./[2]Saleh AF, et, al. 2'-O-(2-Methoxyethyl) Nucleosides Are Not Phosphorylated or Incorporated Into the Genome of Human Lymphoblastoid TK6 Cells. Toxicol Sci. 2018 May 1;163(1):70-78.

CAS Number: 473278-54-5

Molecular Weight: 341.32

Compound Purity: 99.81

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Nucleoside Antimetabolite/Analog

• Artikelnummer: MEXHY-23789-250
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-23789-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK