5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine, CAS 23669-79-6

Product Description: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks[1][2].

Formula: C30H30N2O7

References: [1]Hidalgo-Zarco F, et, al. Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major. Protein Sci. 2001 Jul;10(7):1426-33./[2]Hovinen J, et, al. Versatile strategy for oligonucleotide derivatization. Introduction of lanthanide(III) chelates to oligonucleotides. Org Lett. 2001 Aug 9;3(16):2473-6.

CAS Number: 23669-79-6

Molecular Weight: 530.57

Compound Purity: 98.20

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: DNA/RNA Synthesis

• Artikelnummer: MEXHY-W097792-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W097792-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK