Product Description: 5'-O-Tritylthymidine is an inhibitor of TK-2 and inhibits angiogenesis[1]. 5'-O-Tritylthymidine targets FAK-Mdm-2 interactions, decreasing cell viability and increasing apoptosis.
Formula: C29H28N2O5
References: [1]Hernández A et al. Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. J Med Chem. 2002 Sep 12;45(19):4254-63. /[2]Golubovskaya V et al. A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo. Anticancer Agents Med Chem. 2013 May;13(4):532-45.
CAS Number: 7791-71-1
Molecular Weight: 484.54
Compound Purity: 97.49
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Biochemical Assay Reagents