Formulation: Lyophilized from a solution in PBS, pH 7.4, at 10 mg per vial. Reconstitution with 0.2 ml of water will yield 50 mg/ml solution in 1X PBS
Shelf life (days): 730
Notes: Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars.{38175,38176,38177} AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer’s disease, cataract, and ageing.{38175,38176,38177} AGE receptors, such as the receptor for AGE (RAGE), mediate biological responses to AGEs, including endocytic uptake and degradation and induction of cytokines and growth factors.{38175,38176,38177} AGE-BSA was produced by incubating BSA with glucose, followed by extensive dialysis.