Product Description: Apo-Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin indicates an iron deficient environment, can directly bind to hephaestin, which can convert Fe2+ to Fe3+. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1[1].
Applications: Neuroscience-Neuromodulation
Formula: N/A
References: [1]Baringer SL, et al. Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier. bioRxiv [Preprint]. 2023 Jan 10:2023.01.10.522344.
CAS Number: 11096-37-0
Molecular Weight: N/A
Compound Purity: 95.0
Research Area: Others
Solubility: H2O : 50 mg/mL (ultrasonic)
Target: Ferroportin;Transferrin Receptor