BCN-OH, CAS 1263166-90-0

Product Description: BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps[1].

Formula: C10H14O

References: [1]Li Z, et al. Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function. Chem Res Toxicol. 2019 Mar 18;32(3):526-534.

CAS Number: 1263166-90-0

Molecular Weight: 150.22

Compound Purity: 99.15

Research Area: Others

Solubility: DMSO : 130 mg/mL (ultrasonic)

Target: Biochemical Assay Reagents

• Artikelnummer: MEXHY-W111141-1G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W111141-1G
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK