Product Description: Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
Applications: Cancer-programmed cell death
Formula: C30H49FN6O8S
References: [1]Li J, et al. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem. 1999 Jun 11;274(24):17325-33./[2]Samraj AK, et al. Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membranedepolarization. Mol Biol Cell. 2007 Jan;18(1):84-93.
CAS Number: 1135688-15-1
Molecular Weight: 672.81
Compound Purity: 98.0
Research Area: Cancer
Solubility: DMSO : ≥ 27.3 mg/mL
Target: Caspase