EGTA (tetrasodium), CAS 13368-13-3

Product Description: EGTA tetrasodium is a specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2].

Formula: C14H20N2Na4O10

References: [1]Harris RA, Hanrahan JW. Effects of EGTA on calcium signaling in airway epithelial cells. Am J Physiol. 1994;267(5 Pt 1):C1426-C1434. doi:10.1152/ajpcell.1994.267.5.C1426./[2]Segura-Egea JJ, Jiménez-Rubio A, Rios-Santos JV, Velasco-Ortega E, Calvo-Gutierrez JR. In vitro inhibitory effect of EGTA on macrophage adhesion: endodontic implications. J Endod. 2003;29(3):211-213.

CAS Number: 13368-13-3

Molecular Weight: 468.28

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Biochemical Assay Reagents

• Artikelnummer: MEXHY-D0861A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-D0861A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK