Eniporide, CAS 176644-21-6

Product Description: Eniporide (EMD 96785) is a Na(+)/H(+) exchange (NHE) inhibitor. Eniporide specifically inhibits the NHE-1 isoform. Eniporide improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide regulates cardiac performance and high-energy phosphate content in clinically relevant pig models of CPB and cardiac arrest[1][2].

Formula: C14H16N4O3S

References: [1]Zeymer U, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50. /[2]Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77(2):658-63.

CAS Number: 176644-21-6

Molecular Weight: 320.37

Research Area: Others

Solubility: 10 mM in DMSO

Target: Biochemical Assay Reagents

• Artikelnummer: MEXHY-106150-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-106150-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK