Product Description: Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].
Applications: Cancer-Kinase/protease
Formula: C10H14N2O
References: [1]Strong JM, et al. Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther. 1975 Feb;17(2):184-94.
CAS Number: 18865-38-8
Molecular Weight: 178.23
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug Metabolite;ERK;MEK;NF-κB;Sodium Channel