N,N-Dimethylacetamide, CAS 127-19-5

Product Description: N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease[1][2][3].

Formula: C4H9NO

References: [1]Sundaram S, et al. N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth. Am J Pathol. 2013 Aug;183(2):422-30./[2]Wei ZH, et al. N,N-dimethylacetamide targets neuroinflammation in Alzheimer's disease in in-vitro and ex-vivo models. Sci Rep. 2023 May 1;13(1):7077./[3]Koya JB, et al. FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models. Fortune J Health Sci. 2022;5:499-509.

CAS Number: 127-19-5

Molecular Weight: 87.12

Compound Purity: 99.98

Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: Biochemical Assay Reagents;NF-κB

• Artikelnummer: MEXHY-W042416-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W042416-100
• Green Labware: Nein
• Verpackungseinheit: 100mL
• Mengeneinheit: STK