Taurohyodeoxycholic acid (sodium), CAS 38411-85-7

Product Description: Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

Formula: C26H44NNaO6S

References: [1]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. /[2]Angelico M, et al. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs. Scand J Gastroenterol. 1995 Dec;30(12):1178-85. /[3]Angelico M, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. Dig Dis Sci. 1994 Nov;39(11):2389-97. /[4]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. /[5]Solmon Kusuma S, et al. Antineoplastic activity of monocrotaline against hepatocellular carcinoma[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 2014, 14(9): 1237-1248.

CAS Number: 38411-85-7

Molecular Weight: 521.69

Compound Purity: 98.0

Research Area: Inflammation/Immunology

Solubility: H2O : 62.5 mg/mL (ultrasonic)

Target: Interleukin Related;TNF Receptor

• Artikelnummer: MEXHY-114360A-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-114360A-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK