R18 (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-α-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-α-aspartyl-L-leucyl-L-α-glutamyl-L-alanyl-L-asparaginyl-L-methionyl-L-cysteinyl-L-leucyl-L-proline, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C101H157N27O29S3 • XCF3COOH

Formula Weight: 2309,7

Shelf life (days): 1460

Notes: R18 is a synthetic peptide inhibitor of the protein-protein interaction between 14-3-3 proteins and Raf-1.{66459} It binds to 14-3-3τ, -β, and -ζ (Kds = 7.1, 7, and 8.9 nM, respectively) and inhibits 14-3-3τ binding to Raf-1 in a filter binding assay when used at a concentration of 5 nM. R18 also inhibits 14-3-3ζ-mediated protection of Raf-1 from phosphatase-induced inactivation.

• Artikelnummer: CAY36695-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36695-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK