Sclareolide, CAS 564-20-5

Formulation: A crystalline solid

Formal Name: (3aR,5aS,9aS,9bR)-decahydro-3a,6,6,9a-tetramethyl-naphtho[2,1-b]furan-2(1H)-one

Purity: ≥98%

Formula Markup: C16H26O2

Formula Weight: 250,4

Shelf life (days): 1460

CAS Number: 564-20-5

Notes: Sclareolide is a sesquiterpene lactone that has been found in Salvia and has diverse biological activities.{57254,57255,57257,57258} It inhibits mycelial growth in the phytopathogenic fungi B. cinerea, F. coeruleum, C. lunata, F. graminearum, and A. brassicae by 33.93, 67.14, 27.04, 46.22, and 32.48%, respectively, when used at a concentration of 100 μg/ml.{57255} Sclareolide is an Ebola virus entry inhibitor that reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with Ebola virus glycoprotein (EC50 = 8 μM).{57257} It inhibits nitric oxide production in LPS-stimulated BV-2 cells (IC50 = 20.3 μM).{57258} Sclareolide (5, 10, and 20 μM) enhances gemcitabine-induced cell death in gemcitabine-resistant PANC-1 and AsPC-1 human pancreatic cancer cells.{57254}

• Artikelnummer: CAY31371-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31371-25
• Green Labware: Nein
• Verpackungseinheit: 25 g
• Mengeneinheit: STK