5-Iodotubercidin, CAS 24386-93-4

Formulation: A solid

Formal Name: 5-iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Purity: ≥95%

Formula Markup: C11H13IN4O4

Formula Weight: 392,2

Shelf life (days): 1460

CAS Number: 24386-93-4

Notes: 5-Iodotubercidin is an inhibitor of adenosine kinase (IC50 = 0.026 µM).{66198} It inhibits protein kinase A (PKA), phosphorylase kinase, casein kinase 1 (CK1), CK2, and PKC (IC50s = 5-10, 5-10, 0.4, 10.9, and 0.4 µM, respectively).{15083} 5-Iodotubercidin is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp; EC50 = 0.75 µM).{62876} It decreases fatty acid synthesis and increases fatty acid oxidation in isolated rat hepatocytes when used at a concentration of 20 µM.{15219} In vivo, 5-iodotubercidin reduces the number of seizures in a rat model of seizures induced by maximum electroshock (MES; ED50 = 6 mg/kg).{66198}

• Artikelnummer: CAY10010375-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010375-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: Reinstoffe