Formulation: A crystalline solid
Formal Name: 6-chloro-3-[(1E)-3-[[(2-methoxyphenyl)methyl]amino]-3-oxo-1-propen-1-yl]-1H-indole-2-carboxylic acid, ethyl ester
Purity: ≥98%
Formula Markup: C22H21ClN2O4
Formula Weight: 412,9
Shelf life (days): 730
CAS Number: 2349374-37-2
Notes: 9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 µM).{35962} It decreases LPS- and IFN-γ-induced NF-ĸB activity in RAW-Blue™ cells when used at concentrations of 0.2, 1, and 5 µM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 µM.