Formulation: A solid
Formal Name: N-acetyl-L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C94H158N20O27 • XCF3COOH
Formula Weight: 2000,4
Shelf life (days): 1460
Notes: Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO (Item No. 10017), a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF.{7777,7213,17866} It is an inhibitor of caspase-3 that reduces caspase-3 activity and apoptosis induced by prostaglandin E2 (PGE2; Item No. 14010) in rat cortical neurons when used at concentrations ranging from 1 to 2.5 μM.{46179}