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CAS Number: 2627-69-2
Description: AICAR, also known as acadesine, is an adenosine regulating agent and AMPK activator. AICAR was found to activate AMP-activated protein kinase (AMPK) in skeletal muscle, inhibit acetyl-CoA carboxylase, reduce malonyl-CoA, and increase fatty acid oxidation and glucose uptake. Note: This product is not 5'-phosphorylated.
Format: Tan powder
Purity: ≥99%
Solubility: Soluble in DMSO at 40 mg/ml; soluble in ethanol at 2 mg/ml with warming; soluble in water at 20 mg/ml with warming
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: Merrill, G.F., et al. Am. J. Physiol. 273: E1107-E1112 (1997).