AM580 (GMP), CAS 102121-60-8

Product Description: AM580 (CD336) (GMP) is AM580 (HY-10475) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AM580 is a selective RARα agonist[1][2][3][4].

Applications: Cancer-programmed cell death

Formula: C22H25NO3

References: [1]Zhao T, et al. Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming. Cell Stem Cell. 2018 Jul 5;23(1):31-45.e7. /[2]Cai A, et al. Neuroblastoma SH-SY5Y Cell Differentiation to Mature Neuron by AM580 Treatment. Neurochem Res. 2022 /[3]Gianní M, et al. AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. Blood. 1996 Feb 15;87(4):1520-31./[4]Brok-Volchanskaya VS, et al. Effective and Rapid Generation of Functional Neutrophils from Induced Pluripotent Stem Cells Using ETV2-Modified mRNA. Stem Cell Reports. 2019 Dec 10;13(6):1099-1110.

CAS Number: 102121-60-8

Molecular Weight: 351.44

Compound Purity: 99.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: RAR/RXR

• Artikelnummer: MEXHY-10475G-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10475G-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK