AR-9281, CAS 913548-29-5

Formulation: A solid

Formal Name: N-(1-acetyl-4-piperidinyl)-N′-tricyclo[3.3.1.13,7]dec-1-yl-urea

Purity: ≥95%

Formula Markup: C18H29N3O2

Formula Weight: 319,4

Shelf life (days): 1460

CAS Number: 913548-29-5

Notes: AR-9281 is an inhibitor of soluble epoxide hydrolase (sEH; IC50 = 7 nM for the human enzyme).{65781} It reduces LPS-induced increases in plasma levels of dihydroxyeicosatrienoic acids (DiHETs), prostaglandin E2 (PGE2; Item No. 14010), and PGD2 (Item No. 12010) in rats when administered at a dose of 3 mg/kg.{65782} AR-9281 (1 and 3 mg/kg) inhibits LPS-induced allodynia in a rat model of inflammatory pain and increases the paw withdrawal threshold in a rat model of diabetic neuropathic pain induced by streptozotocin (Item No. 13104).

• Artikelnummer: CAY38346-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38346-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK