BTSA1, CAS 314761-14-3

Formulation: A solid

Formal Name: 3-phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione, 4-[2-(2-thiazolyl)hydrazone]

Purity: ≥98%

Formula Markup: C21H14N6OS2

Formula Weight: 430,5

Shelf life (days): 1460

CAS Number: 314761-14-3

Notes: BTSA1 is an activator of Bax.{72077} It binds to the Bax N-terminal activation site, also known as the trigger site (IC50 = 250 nM), and induces Bax translocation membrane permeabilization in liposomes when used at concentrations ranging from 100 to 400 nM. BTSA1 (0.1-1 µM) induces apoptosis in various human and mouse acute myeloid leukemia (AML) cell lines. In vivo, BTSA (10 mg/kg) reduces bone marrow infiltration and promotes apoptosis in bone marrow infiltrates in a MOLM-13 AML mouse xenograft model.

• Artikelnummer: CAY37305-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37305-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK