Formulation: A crystalline solid
Formal Name: N-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-L-phenylalanine, methyl ester
Purity: ≥98%
Formula Markup: C19H19NO4
Formula Weight: 325,4
Shelf life (days): 1460
CAS Number: 615264-52-3
Notes: Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.{10960,11758} CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 µM.{12441} It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 µM.{12441}