Formulation: A solid
Formal Name: 2-(2-propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]-phenol
Purity: ≥98%
Formula Markup: C20H23N3O
Formula Weight: 321,4
Shelf life (days): 1460
CAS Number: 692269-09-3
Notes: CM10 is a pan-aldehyde dehydrogenase 1 (ALDH1A) inhibitor (IC50s = 1,700, 740, and 640 nM for human ALDH1A1, ALDH1A2, and ALDH1A3, respectively).{57962} It is selective for ALDH1A isoforms over ALDH2, -3A1, -4A1, -5A1, -1B1, and -1L1 at 20 µM. CM10 induces necroptosis in ovarian cancer stem cells.