Curcumin analog C1, CAS 39777-61-2

Formulation: A solid

Formal Name: (1E,4E)-1,5-bis(2-methoxyphenyl)-1,4-pentadien-3-one

Purity: ≥98%

Formula Markup: C19H18O3

Formula Weight: 294,3

Shelf life (days): 1460

CAS Number: 39777-61-2

Notes: Curcumin analog C1 is a synthetic curcuminoid.{64000,64001} It inhibits the proliferation of HCT116 colon cancer cells (GI50 = 4 µM).{64000} Curcumin analog C1 (1 µM) activates transcription factor EB (TFEB), inducing nuclear translocation in Neuro2a mouse neuroblastoma cells.{64001} It increases LC3-II levels and promotes autophagic flux in Neuro2a cells when used at a concentration of 1 µM. Curcumin analog C1 (10 and 25 mg/kg, p.o.) activates TFEB and increases autophagy and lysosome biogenesis in rat brain.

• Artikelnummer: CAY34255-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34255-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe