DC-LC3in-D5, CAS 2868312-73-4

Formulation: A crystalline solid

Formal Name: 5-(2,3-dichlorophenyl)-2-[[[2-(4-morpholinyl)ethyl]amino]methylene]-1,3-cyclohexanedione

Purity: ≥95%

Formula Markup: C19H22Cl2N2O3

Formula Weight: 397,3

Shelf life (days): 730

CAS Number: 2868312-73-4

Notes: DC-LC3in-D5 is an inhibitor of LC3 (IC50 = 200 nM).{55946} It selectively binds to LC3-I and LC3-II over GABA type A receptor-associated protein (GABARAP), scavenger receptor class B member 2 (SCARB2), and paraoxonase 2 (PON2) in an activity-based protein profiling (ABPP) assay using HeLa cells. DC-LC3in-D5 (25 µM) inhibits LC3-II lipidation, autophagosome formation, and the protein-protein interaction between LC3-II and ATG7 in HeLa cells.

• Artikelnummer: CAY38339-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38339-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK