DL-erythro-PDMP (hydrochloride), CAS 80943-40-4

Formulation: A solid

Formal Name: rel-N-[(1R,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride

Purity: ≥98%

Formula Markup: C23H38N2O3 • HCl

Formula Weight: 427

Shelf life (days): 1460

CAS Number: 80943-40-4

Notes: DL-erythro-PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP (Item No. 62595): D-erythro-(1S,2R)-PDMP and L-erythro-(1R,2S)-PDMP.{11392,62049} It protects glucosylceramide (GlcCer) synthase from degradation and increases the level of ceramide in MDCK cells when used at a concentration of 40 µM.{62049} Unlike DL-threo-PDMP, DL-erythro-PDMP does not inhibit GlcCer synthase, but it does inhibit UDP galactose:ceramide galactosyltransferase by 27% in mouse brain microsomes when used at a concentration of 100 µM.{11341} It inhibits the growth of isolated rabbit skin fibroblasts when used at a concentration of 50 µM but is cytotoxic at concentrations higher than 50 µM.{62050} [Matreya, LLC. Catalog No. 1755]

• Artikelnummer: CAY22676
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22676-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK
• Methode: Reinstoffe