Donepezil HCl , CAS 120011-70-3

Products from BPS Bioscience require a minimum order value above 400€

Background: Donepezil HCl is a piperidine-class AChE inhibitor containing an N-benzylpiperdine and an indanone moiety, which confers it a longer and more selective action against AchE as compared to BuChE (IC50: 7.4 µM). Donepezil HCl has been shown to improve cognitive function of mild to severe moderate AD patients and exhibits excellent tolerability without hepatotoxicity.

CAS Number: 120011-70-3

Solubility: Insoluble in EtOH; insoluble in DMSO; ≥10.4 mg/mL in H2O. For obtaining a highersolubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Target: acetylcholinesterase (AChE)

Biosafety Level: Not applicable (BSL-1)

References: Birks, J., Harvey, R.J . Cochrane Database Syst Rev. 2006 Jan 25;(1):CD001190.

• Artikelnummer: BPS27619-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27619-2
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK