DX3-213B, CAS 2749555-66-4

Formulation: A crystalline solid

Formal Name: (R)-(4,4-difluoropiperidin-1-yl)(1-((4-(isopropylsulfonyl)phenyl)sulfonyl)piperidin-3-yl)methanone

Purity: ≥95%

Formula Markup: C20H28F2N2O5S2

Formula Weight: 478,6

Shelf life (days): 730

CAS Number: 2749555-66-4

Notes: DX3-213B is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50 = 3.6 nM).{62736} It inhibits the proliferation of MiaPaCa-2 cells cultured in galactose- but not glucose-containing media (IC50s = 9.1 and >3,000 nM, respectively). DX3-213B (10 mg/kg) reduces tumor volume in a Panc02 murine pancreatic ductal adenocarcinoma model.

• Artikelnummer: CAY36783-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36783-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe