Epacadostat (INCB024360), CAS 1204669-58-8

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Biological Activity: Epacadostat has been reported to restore and increase the proliferation ofvarious immune cells including dendritic cells, NK cells, and T cells in vitro and in vivo.

CAS Number: 1204669-58-8

Description: Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC₅₀ of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Epacadostat displays potential immunomodulating and antineoplastic activities.

Format: White powder

Purity: ≥98%

Solubility: Soluble in DMSO.

Storage Stability: Store as supplied at or below -20°C for up to 2 years. Stable in DMSO at-80°C for up to 6 months.

Biosafety Level: Not applicable (BSL-1)

References: 1. Koblish, HK., et al., Molec. Cancer Therapeutics. 2010; 9: 489-498.

• Artikelnummer: BPS27339-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27339-2
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK