FOXM1 Inhibitor III, CAS 313380-27-7

Formulation: A solid

Formal Name: 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)-thieno[2,3-b]pyridine-2-carboxamide

Purity: ≥98%

Formula Markup: C19H11F4N3OS2

Formula Weight: 437,4

Shelf life (days): 1460

CAS Number: 313380-27-7

Notes: FOXM1 inhibitor III is an inhibitor of the DNA-binding activity of forkhead box protein M1 (FOXM1; IC50 = 22.5 µM).{69118} It binds to FOXM1 and is selective for inhibiting FOXM1 transcriptional activity over FOXA1, FOXA2, FOXP2, and GATA-binding factor 1 (GATA-1) transcriptional activity. FOXM1 inhibitor III inhibits the growth of MCF-7 and MDA-MB-231 breast and PEO1 ovarian cancer cells (GI50s = 18, 21.8, and 18.1 µM, respectively).

• Artikelnummer: CAY36932-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36932-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe