GDC-0941 , CAS 957054-30-7 

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Biological Activity: GDC-0941 against p110a IC50=0.003µM. The IC50 for inhibiting cell proliferation in PC3 (prostate cancer) or U87MG (glioma) cells is 0.28 µM and 0.95 µM, respectively.

CAS Number: 957054-30-7 

Description: GDC-0941, also known as Pictilisib, is a phosphatidylinositol 3-kinase (PI3K) inhibitor

Format: Solid

Purity: ≥99% by HPLC.

Solubility: Soluble in DMSO at 66 mg/ml; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µg

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Biosafety Level: Not applicable (BSL-1)

References: 1. Folkes, A.J. et al. J. Med. Chem. 51: 5522-5532 (2008)
2. Yao, E. et al. Clin. Cancer Res. 15: 4147-4156 (2009)

• Artikelnummer: BPS27000
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27000
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK