GK241, CAS 1899930-93-8

Formulation: A crystalline solid

Formal Name: N-(1,2-dioxohexadecyl)-L-valine

Purity: ≥98%

Formula Markup: C21H39NO4

Formula Weight: 369,5

Shelf life (days): 730

CAS Number: 1899930-93-8

Notes: GK241 is a secretory phospholipase A2 (sPLA2) (Type IIA) inhibitor (IC50s = 0.143 and 0.068 µM for the human and mouse enzymes, respectively).{62887,62888} It inhibits IL-1β-induced production of prostaglandin E2 (PGE2; Item No. 14010) in isolated rat renal mesangial cells when used at concentrations of 3 and 10 µM.{62889} GK241 also inhibits the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro; IC50 = 24 µM).{62887}

• Artikelnummer: CAY37689-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37689-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe