HA-1077 , CAS 203911-27-7

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CAS Number: 203911-27-7

Description: Dihydrochloride form of HA-1077. Inhibits a number of kinases, including ROCK I (IC50 = 10.7 µM), ROCK II (IC50 = 1.9 µM), MAPK1 (IC50 = 5 µM), and PKCRK2 (IC50 = 4 µM). Weaker inhibitor of PKC (IC50 = 425 µM) and MLCK (IC50 = 95 µM) .

Format: White crystalline powder.

Purity: ≥99%

Solubility: Very soluble in water, up to 200 mg/ml or more; soluble in DMSO up to about 10 mg/ml; not soluble in ethanol; addition of an aqueous solution of this dihydrochloride salt into a buffer solution may significantly alter its solubility

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Biosafety Level: Not applicable (BSL-1)

References: Davies, S.P. et al. Biochem. J. 351: 95-105 (2000).

• Artikelnummer: BPS27030
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27030
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK