Hexa-D-Arginine (trifluoroacetate salt)

Formulation: A solid

Formal Name: D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C36H75N25O6 • XCF3COOH

Formula Weight: 954,1

Shelf life (days): 1460

Notes: Hexa-D-arginine is an inhibitor of the proprotein convertase furin (Ki = 100 nM).{62737} It also inhibits West Nile virus nonstructural protein 3 (NS3) protease (Ki = 478 nM). Hexa-D-arginine (1 µg/ml) reduces the proliferation, invasion, and migration of SW 1990 and PaTu 8988 pancreatic cancer cells, as well as decreases the levels of N-cadherin and vimentin and increases E-cadherin levels, markers of the epithelial-to-mesenchymal transition (EMT), in the same cells.{62738} It improves survival in a rat model of anthrax toxemia induced by the anthrax toxins protective antigen and lethal factor.{62739}

• Artikelnummer: CAY36065-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36065-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe