HMN-176, CAS 173529-10-7

Formulation: A solid

Formal Name: 4-methoxy-N-[2-[(1E)-2-(1-oxido-4-pyridinyl)ethenyl]phenyl]-benzenesulfonamide

Purity: ≥98%

Formula Markup: C20H18N2O4S

Formula Weight: 382,4

Shelf life (days): 1460

CAS Number: 173529-10-7

Notes: HMN-176 is an anticancer agent and active metabolite of the prodrug HMN-214 (Item No. 26210).{43655} It is cytotoxic against a panel of cancer cell lines with a mean IC50 value of 112 nM, as well as P388 leukemia cells that are resistant to the DNA-crosslinking agent cisplatin (Item No. 13119), anthracycline antitumor antibiotic doxorubicin (Item No. 15007), or antimitotic vincristine (Item No. 11764) (IC50s = 143, 557, and 265 nM, respectively). HMN-176 (3 µM) induces cell cycle arrest at the G2/M phase in HeLa cervical cancer cells.

• Artikelnummer: CAY37424-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37424-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK